Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum

نویسندگان

  • Wenhui Wu
  • Keiji Hasumi
  • Hui Peng
  • Xianwen Hu
  • Xichang Wang
  • Bin Bao
چکیده

Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(alpha-D-glucopyranosyl)-glycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(alpha-D-glucopyranosyl)-glycerol (MOGG) which were obtained from Sargassum fulvellum for the first time. POGG and MOGG showed fibrinolytic activity in the reaction system of pro-u-PA and plasminogen.

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عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2009